Recently, it has been shown that the Mitochondrial aldehyde dehydrogenase is responsible for the bioactivation of nitroglycerin prior to the release of NO, which is a strong vasodilator.
近来,有研究表明粒体乙醛
是体内催化硝酸甘油生物转化的主要
,
粒体乙醛
同时具有
和酯
的催化活性,其酯
活性可以通过将硝酸甘油
硝形成一氧化氮,进而血管扩张。