Recently, it has been shown that the Mitochondrial aldehyde dehydrogenase is responsible for the bioactivation of nitroglycerin prior to the release of NO, which is a strong vasodilator.
近来,有研究粒体乙醛脱氢
是体内催
硝酸甘油生物转
的主要途径,
粒体乙醛脱氢
同时具有脱氢
的催
活性,其
活性可以通过将硝酸甘油脱硝形成一氧
氮,进而血管扩张。