Abstract: Phospholamban (PLB) is a prominent regulator of myocardial contractility and a reversible inhibitor of the cardiac sarcoplasmic reticulum Ca2+ ATPase activity.
受磷蛋白(phospholamban)是心收缩的一个重因子,可抑制心钙ATPase的活性、降低其对钙的亲和力。
Abstract: Phospholamban (PLB) is a prominent regulator of myocardial contractility and a reversible inhibitor of the cardiac sarcoplasmic reticulum Ca2+ ATPase activity.
受磷蛋白(phospholamban)是心收缩的一个重因子,可抑制心钙ATPase的活性、降低其对钙的亲和力。
In normal cardiac muscles, phospholamban can be phosphorylated at distinct sites by various protein kinases and release its inhibition to sarcoplasmic reticulum Ca2+ ATPase.
正情况下,受磷蛋白可被不同的蛋白激酶磷酸化从而解除其钙ATPase的抑制作用。
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