phocomelia

1961年,明确发现沙度胺可引起婴儿海豹肢畸及无肢畸,导致该药迅速撤出市场。

It was removed from the market in 1961 after it was associated with an epidemic of severe birth defects: phocomelia and amelia.

In 1961 it was found to cause congenital disorders;when it is taken in early pregnancy, some 20% of fetuses develop phocomelia (see agenesis) and other deformities;5,000∼10,000 such babies were born.

1961年则发现其可导致先性疾病，在妊娠早期应用沙，约20%胎儿可发海豹肢畸（参阅agenesis）及其他畸，有5,000∼10,000名这种畸儿出。