Levocetirizine Dihydrochloride was prepared from benzoyl chloride by acidylation,hydrogenation,cyclization with an overall yield of 8.05%.
以苯甲酰氯为原料,经酰化,还原,环应
成左旋西替利嗪盐酸盐,
应总收率为8.05%。
Levocetirizine Dihydrochloride was prepared from benzoyl chloride by acidylation,hydrogenation,cyclization with an overall yield of 8.05%.
以苯甲酰氯为原料,经酰化,还原,环应
成左旋西替利嗪盐酸盐,
应总收率为8.05%。
, and the production and application of it were described.At present, the methods of synthesizing N-formylmorpholine are formic acid method, methyl formate method, carboxide acidylation method, etc.
目前N-甲酰吗啉的要
方法有甲酸法、甲酸甲酯法和羰基
成法
,其中甲酸法
工艺最优,有较好的工业应用前景。
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