The most common pre-hepatic cause is portal vein obstruction, like when there's a thrombus occluding the portal vein and blocking blood flow.

最常见的肝前型病因是门静阻塞，例如当有栓子阻塞门静时。

Embolism is the mobilization of a thrombus, a clot.

栓塞是栓、块的活动。

Long-term treatment to prevent future thrombi from forming can include anticoagulant medications like warfarin or heparin, which inhibit the clotting cascade and prevent clot formation.

预防DVT的长期疗法包括华法林、肝素等抗凝药物的，以阻断凝反应。

Endothelial injury also leads to the formation of lots of tiny thrombi in the microvasculature, a process that uses up massive amounts of platelets.

内皮损伤还导致微形成大量微小栓，这一过程将消耗大量小板。

Finally, with protein C or S deficiency, there can be warfarin induced skin necrosis, which means tiny thrombi can form in the blood vessels of the skin, causing skin necrosis.

此外，患者身上还能出现华法林导致的皮肤坏死，也就是说在皮肤中形成小栓，导致皮肤坏死。