In mice, widespread deletion of the tumor suppressor Phosphatase and tensin homolog (PTEN) generates hamartomatous intestinal polyps with epithelial and stromal inolement.
在小鼠,广泛的删除肿瘤抑磷酸酶和张蛋白同源物〔PTEN〕构的小肠隐窝,含有上皮和间质。
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MSCs differentiate into adipocytes, osteocytes, chondrocytes, tenocytes, marrow stromal cells, muscle, and perhaps neuronal cells and are being used in early clinical trials to enhance bone marrow grafting and to suppress graft-versus-host disease in allogeneic bone marrow transplants.
MSCs分化成脂肪,,软,肌腱,基质,肌肉和神经,并用于早期临床试验,以增强移植和抑制同种异体移植中的移植物抗宿主病。