But unfortunately, it's incredibly difficult to reengineer the constrained peptides that we find in nature to become new drugs.

但不幸是，要想重组自然界中性肽，将其成新药，是异常难。

How do we define nature when we can reengineer its properties, and when should we do it?

可以重新设计自然属性时， 如何定义自然，什么时候应该这样做？

I decided to reengineer the process through some classic business tools.

决定通过一些经典商业工具重新设计流程。