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This is the appearance of normal bone marrow smear at high magnification. Note the presence of an eosinophilic myelocyte, a basophilic myelocyte, and a plasma cell.

高倍镜下的正涂片,可见个嗜酸性细胞,个嗜碱性细胞和浆细胞

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Osmosis-血液肿瘤

Some of these activated B-cells mature directly into plasma cells and produce IgM antibodies.

其中一些的B细胞直接成熟分化为浆细胞并产生IgM抗体。

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Osmosis-血液肿瘤

Plasma cells release antibodies or immunoglobulins.

浆细胞可以分泌抗体,即免疫球蛋白。

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Osmosis-血液肿瘤

B-cells differentiate into plasma cells, which are found in the medulla or center of the lymph node.

B细胞分化为浆细胞浆细胞存在于淋巴结的髓质(淋巴结的中心)。

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博兹曼科学——生物

So it can make plasma cells.

因此,它能够造浆细胞。

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Osmosis-解剖与生理

When a T cell gets activated it helps the B cell mature into a plasma cell, and a plasma cell can secrete lots and lots of antibodies.

当T细胞时,它也会帮助B细胞成熟为浆细胞;浆细胞会分泌大量的抗体。

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NEJM This Week

The diagnosis of progression to cancer, or MGCS, usually requires histopathological confirmation to ensure that the clinical problem is attributable to the plasma cell disorder.

癌症进展或意义未明的单克隆免疫球蛋白病综合征(MGCS)的诊断,通常需要组织病理学证实,以确保题可归因于浆细胞异常。

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NEJM This Week

Monoclonal gammopathy of undetermined significance, MGUS, is a premalignant plasma cell disorder present in approximately 5% of the general population over the age of 50 years.

意义未定的单克隆免疫球蛋白病(MGUS)是一种存在于50岁以上人群中约5%的癌前浆细胞疾病。

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Crash Course 解剖生理学篇

Others run defense for you, like the gamma globulin antibodies that are released by plasma cells during an immune response, or fibrinogen proteins, which are vital to forming blood clots and stopping bleeding.

另一些则为你提供防御,比如免疫反应期间浆细胞释放的丙种球蛋白抗体,或者对形成血凝块和止血至关重要的纤维蛋白原蛋白。

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NEJM This Week

MGUS is characterized by the presence of detectable monoclonal M proteins, which are identical copies of intact immunoglobulins, immunoglobulin light chains, or both, that are secreted by the clonal plasma cells.

单克隆免疫球蛋白病未定性(MGUS)的特征在于可检测到的单克隆M蛋白存在,这些M蛋白是完整的免疫球蛋白、免疫球蛋白轻链或两者的完全相同副本,由克隆性浆细胞分泌。

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Osmosis-解剖与生理

B cells are designed to only react to foreign antigens, and if the dendritic cell presents something foreign, the B cell turns into a plasma cells and starting cranking out antibodies which then flow into the lymph and exit the lymph node.

B细胞仅仅用于对异体抗原起反应,并且如果树突状细胞呈递异体物质,B细胞就会转变为浆细胞,开始造抗体而抗体随淋巴流出淋巴结。

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