One of the most popular decongestant ingredients is phenylephrine.

减充血剂最常见成分之一是苯肾上腺素。

Exactly. So, more products started using phenylephrine.

没错。于是更多的产开始使用苯肾上腺素。

But I didn't know there was anything wrong with phenylephrine.

但我不知道苯肾上腺素有什么问题。

We'll make phenylephrine red because we know it leaves you congested.

我们会让苯肾上腺素的成像变红，因为我们知道它会让你充血。

And I always look to see if a decongestant like phenylephrine is in the capsule.

我总是看胶囊成分，是否含有像苯肾上腺素这样的减充血剂。

Overall, though, if oral phenylephrine doesn't work, what should people use instead of it?

总的来说，如果口服苯肾上腺素不起作用，还有什么更好的替代？

Yep. Phenylephrine was actually approved in the 1970s, so it had been around a while.

是的。苯肾上腺素实际上是在20世纪70年代获批的，所以它已经存在了一段时间了。

Scientists who advise the FDA recently concluded that phenylephrine, a common decongestant in cold medicines, doesn't work.

美国食和药管理局(FDA)的顾问家最近得出结论：感冒药中常见的减充血剂苯肾上腺素不起作用。

It led to further similarly conclusive studies that phenylephrine was ineffective.

这导致了进一步类似的结论性研究，即苯肾上腺素是无效的。

The take-home messages are oral phenylephrine is inaffective as a nasal decongestant but safe.

带回家的信息是口服苯肾上腺素作为减充血剂是无效的，但安全。

Where nasal congestion went down after taking pseudoephedrine and went like this for a placebo and phenylephrine.

服用伪麻黄碱后鼻塞减轻，服用安慰剂和苯肾上腺素后鼻塞也减轻。

" 10 milligrams of phenylephrine works no better than a placebo."

“10 毫克苯肾上腺素的效果并不比安慰剂好。”

She was on the recent FDA advisory panel earlier this month that made the decision that phenylephrine wasn't effective.

她是本月早些时候做出苯肾上腺素无效决定的FDA顾问小组的专家。

By 1976, they'd convened a looser review and a panel recommended Phenylephrine as an oral, nasal decongestant.

到 1976 年，他们召集了一个较为宽松的审查小组，并建议将苯肾上腺素作为口服鼻塞解充血剂。

So, the committee voted unanimously that oral phenylephrine is basically useless.

因此，委员会一致认为口服苯肾上腺素并无缓解鼻塞的功效。

And the panelists voting, they seemed a little mystified by how we got to a point where phenylephrine took over.

小组成员投票时，他们似乎有点困惑，为什么我们会走到苯肾上腺素占据主导地位的地步。

So, more products started using phenylephrine.

因此，更多的产开始使用去氧肾上腺素。

Phenylephrine was actually approved in the 1970s, so it had been around a while.

去氧肾上腺素实际上是在 20 世纪 70 年代获得批准的，所以它已经存在了一段时间了。

Taken from an FDA Zoom meeting these are the votes of FDA panel members on whether phenylephrine is effective.

摘自 FDA Zoom 会议这些是 FDA 小组成员对苯肾上腺素是否有效的投票。

They have known for decades that phenylephrine might not really work and it's just the process that's gotten in the way.

他们几十年前就知道苯肾上腺素可能并没有真正起作用，只是这个过程阻碍了治疗。