These three are all technically monoamines but norepinephrine and dopamine are classified as catecholamines.

严格说来，这三激素都属于单胺，但去甲肾上腺素和巴胺也被归为儿茶酚胺。

I'm leading a study to see if deficiency of the monoamine oxidase enzyme leads to paralyzing fear in monkeys.

我将带领团队研究单胺氧化酶缺失是否会导致猴子精神崩溃。

You know, not a lot of people know this, but the monoamine oxidase enzyme was discovered by a woman, Mary Bernheim.

人都不知道这个单胺氧化酶是由一位名叫玛丽·伯恩海姆女性发现。

Both drugs affected a class of neurotransmitters called monoamines.

这两药物都会影响一称为单胺神经递质。

Two of the older classes are called the monoamine oxidase inhibitors and the tricyclic antidepressants.

其中两个较早称为单胺氧化酶抑制剂和三环抗抑郁药。

These two so-called " antidepressants" blocked the usual depletion of the catecholamines dopamine and norepinephrine and blocked the depletion of the monoamine serotonin.

这两所谓“抗抑郁药”阻止了儿茶酚胺、巴胺和去甲肾上腺素消耗，也阻止了 5-羟色胺这单胺消耗。

Very similarly, there are medications like selegiline which inhibits monoamine oxidase B, also known as MAO-B, which is another enzyme that metabolizes dopamine.

似地，像司来吉兰等药物可以抑制单胺氧化酶B，即MAO-B，另一可以分解代谢巴胺酶。

Ipronaizid, imipramine, and other drugs like them were thought to restore that balance by increasing the availability of monoamines in the brain.

异丙肼、丙咪嗪和其他似药物被认为可以通过增加大脑中单胺可用性来恢复这平衡。

In the 1970s, several different researchers converged on an answer: the most effective antidepressants all seemed to act on one monoamine called serotonin.

在 20 世纪 70 年代，几位不同研究人员得出了一个答案：最有效抗抑郁药似乎都作用于一叫做血清素单胺。

The discovery of these antidepressant drugs gave rise to the chemical imbalance theory, the idea that depression is caused by having insufficient monoamines in the brain's synapses.

这些抗抑郁药物发现引发了化学失衡理论，认为抑郁症是由于大脑突触中单胺不足引起。

These drugs targeted several different monoamines, each of which acted on a wide range of receptors in the brain.

这些药物针对几不同单胺药物，每一单胺药物都作用于大脑中受体。

Hoping to make the drugs more targeted and reduce side effects, scientists began studying existing antidepressants to figure out which specific monoamines were most associated with improvements in depression.

为了使药物更有针对性并减少副作用，科学家们开始研究现有抗抑郁药，以确定哪些特定单胺与抑郁症改善最相关。

We're also not sure why antidepressants work the way they do: they change monoamine levels within a few hours of taking the medication, but patients usually don't feel the benefit until weeks later.

我们也不确定为什么抗抑郁药会以它们方式起作用：它们会在服用药物后几个小时内改变单胺水平，但患者通常要到几周后才会感受到好处。