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Here we present the first genome-wide, single-base-resolution maps of methylated cytosines in a mammalian genome, from both human embryon...

DNA cytosine methylation is a central epigenetic modification that has essential roles in cellular processes including genome regulation, development and disease.

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相似单词

3G, 401(K), a,

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原声例句
经济学人-技

The consequence is to inactivate the gene being methylated.

甲基化作用将使甲基化的基因失去。

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学60秒-学美国人 2020年11月合集

As we age, some stretches of DNA get more methylated, and others less.

随着年龄的增长，一些DNA片段的甲基化程度会上升，而另一些则会下降。

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新概念英语.英音版.第四册(译文)

Beware of methylated alcohol, which is very poisonous and should never be added to drinking water.

要提防甲基化酒精，那是剧毒的，永远不能掺入饮用水。

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经济学人-技

Newborns whose mothers suffered from depression while they were pregnant are known to have more highly methylated glucocorticoid-receptor genes than others.

新生儿的母亲若是在孕期间出现抑郁症状，他们糖皮质激素受体基因的甲基化程度就会比其他新生儿更高。

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像学家一样思考（视频版）

I'm using methylated spirits, and it needs to be in the freezer for half an hour before you start the experiment.

我打算使用甲基化酒精，它需要在冰箱里放置半个小时才能开始实验。

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经济学人-技

They found that women abused during pregnancy were significantly more likely than others to have a child with methylated glucocorticoid-receptor genes.

研究发现，孕期中待的母亲生下糖皮质激素受体基因被甲基化的幼儿的可能要比其他母亲高出得多。

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TED演讲（视频版） 2017年3月合集

What you see is the genes that got more methylated are red. The genes that got less methylated are green.

你看的是甲基化程度更高的基因是红色的。甲基化程度较低的基因呈绿色。

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Osmosis-遗传

Translocations can disrupt SNRNP and move the small nucleolar RNA genes away from their imprinting center, causing them to get methylated and turned off.

SNRNP基因易位会破坏小核内核糖核蛋白（SNRPN），并将核仁小RNA基因移出印记中心，导致这些基因的甲基化沉默。

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Osmosis-遗传

If the paternal imprinting center is mutated, the region gets methylated and those genes get turned off, meaning that both the maternal and paternal genes are silenced.

如果父源印记中心突变，基因将被甲基化沉默，导致母源和父源基因都处于沉默状态。

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TED-Ed（视频版）

In one famous experiment, when mother rats weren't attentive enough to their pups, genes in the babies that helped them manage stress were methylated and turned off.

在一个着名的实验中，当母老鼠对它们的幼崽不够关心的情况下，幼崽体内帮助它们管理压力的基因甲基化并且隐藏了。

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If both copies of chromosome 15 were derived from the mother, that means all the prader willi genes are methylated and silenced, since there's no unsilenced paternal genes.

如果15号染色体的两条同源染色体都来自母方，就意味着所有的普拉德-威利基因都被甲基化沉默，根本就没有父源基因的表达。

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