Other causes include metabolic disorders like nonketotic hyperglycemia; and mutations in the genes coding for normal development of the neurons.

其他原因包括代谢紊乱，非酮类高血糖以及编码控制神经元正常发育的基因发生突变。

When that fails to happen, it’s called insulin resistance or hyperglycemia.

果这种情况没有发生， 则为胰岛素抵抗或高血糖。

In this case, though, it's a slower process since there's also an osmotic diuresis or increased urination from the hyperglycemia, or high blood sugar.

尽管在这种情况下，过程较为缓慢，因为也存在渗透性利，或因高血糖而引起的排增多。

As beta cells are lost and insulin levels decrease, glucose levels in the blood start to increase, and patients develop hyperglycemia, which leads to similar clinical signs that I mentioned before, like polyphagia, glycosuria, polyuria, and polydipsia.

丧失β细胞后，胰岛素水平开始下降，血糖水平开始上升，而患者出现高血糖，最终导致之前提及的临床表现，即多食、糖、多与多饮。