The THFA product of hydrogenation in common pressure has been used in enzymatic reaction and expressed the same result as that of THFA from Sigma, the cost of reduction by hydroborates is lower.

常压氢化法已用来代替进口试剂作为酶反应辅酶，但硼氢化物还原法最低，且能合满足酶反应要求物。