CAG codes for the amino acid glutamine, so people with Huntington disease patients will have 36 or more glutamines in a row in the huntingtin protein.
因为CAG序列对应的是谷氨胺(氨基酸),所以在HD内,huntingtin蛋白上会有36个以上连续的谷氨胺。
In some cases, the involved gene contains a triplet repeat where the nucleotides C, A and G are repeated multiple times in a row and since CAG codes for the amino acid glutamine, the encoded protein will have multiple extra glutamines in a row.
在某些情况下,涉及的基因包含一个三联重复序列,即核苷酸C、A和G连续重复多次;由于CAG编码谷氨胺,编码的蛋白将具有连续多个额外的谷氨胺。