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Results A 13389G deletion in exon 6 was characterized in propositus, and this mutation led to frameshift.

结果先证者表现为酶基外显613389G失,引起移码突变。

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Osmosis-肌骨

By comparison, most genes have only about 10 exons and are 50 thousand base pairs in length.

相对来说,大多数基因只有10个外显子和50kbp长。

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Osmosis-肌骨

Most of these gene mutations are deletions or duplications of one or more exons, and a small amount are point mutations.

基因突变大多数为一个多个外显子复,小部分是点突变。

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Osmosis-肌骨

Alright, so the dystrophin gene is a huge gene on the X-chromosome, that has 79 exons and is over 2 million base pairs in length.

抗肌萎缩蛋白基因是X染色体上一个庞大基因,含有79个外显子,全长超过2000kbp(书上通常缩写为bp,碱基对)。

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Osmosis-肌骨

More base pairs and more exons mean that there are more chances for mistakes during meiosis, which is when the egg or sperm are being created.

更多碱基对和外显子意味着减数分裂时有更多出错可能,导致生成X染色体上有错误编码序列卵细胞者精子。

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