Methods The expression of FHIT and PCNA protein in 10 normal endometria, 16 endometrial atypical hyperplasia and 44 endometrial carcinoma tissues was observed by immunohistochemical S-P method.
So having high levels of estrogen will cause the endometrium undergoes hyperplasia, leading to increased risk of developing type 1 endometrial carcinoma.
It's followed by the proliferative phase, during which the rising levels of ovarian estrogen make the functional layer of the endometrium thicken and sprout endometrial glands.
The most common is Type 1 endometrial carcinoma, which is also called endometrioid carcinoma because the tumours grow in a way that looks like normal endometrial glands.
Each time ovulation doesn't result in a healthy pregnancy, the womb gets rid of its endometrial lining, along with any unfertilized eggs, sick, dying, or dead embryos.