Conclusion Melanosis coli is inflammation,benign,reversibility chromatosis as characteristic,the disease is related to taking anthracene for long time constipation.
The reasons were related to emotion, weary, internal damage of food and drink, common cold, constipation, induced abortion, irregular menses and englobement of estrogens.
Toxic metabolites also affect the autonomic nervous system regulating gastrointestinal motility, and this can causes abdominal pain, constipation, and vomiting.