Method The target compound was synthesized from clarithromycin via hydrolyzation,acetylation,cyclic carbonatation,oxidation,decarbonatation,acylation,cyclic carbamatation and cyclization.

方法以克拉霉始原料,经水解、乙、碳酸、氧、脱碳酸、、氨基甲酸和合等反应合成目标合物。