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CONCLUSION: Base pair substitution mutation and frame shift mutation were caused by folpet in Ames test.And DNA breakage in human PMNC might be induced by folpet.

灭菌丹鼠伤寒沙门氏菌碱基置换和码突变,并能损伤人外周血胞DNA的完整性。

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Vox 观点

There are about 3 billion base pairs in our genetic code.

在我们的遗传密码中大约有30亿个碱基对

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Reel知识卷轴

This does not require changing every single base pair in the genome to mammoth.

这不需要将基因组中的每一个碱基对都改变为猛犸象。

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Vox 观点

Of these 3 billion base pairs, 99.9% are exactly the same in all humans.

在这30亿个碱基对99.9%的碱基对在人类中完全相同。

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PBS

Today, any two humans only differ by about 1 out of 1000 DNA base pairs.

如今,意两个人的差别只有千分之一的 DNA 碱基对。

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Osmosis-肌骨

By comparison, most genes have only about 10 exons and are 50 thousand base pairs in length.

相对来说,大多数基因只有10个外显子和50kbp长。

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TED-Ed(视频版)

In each case, the fragments were arbitrarily broken up into small, overlapping pieces about 1,000 base pairs long.

所有实验中,基因片段都被意分割为更小的,有重叠部分的1000个碱基对

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VOA慢速英语_

Each of these base pairs are contained in 23 pairs of chromosomes found in the nucleus of human cells.

这些碱基对中的每一个都包含在人类细胞核里的23对染色体当中。

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TED演讲(音频版) 20179合集

But look at that one base pair.

但是看看那个碱基对。

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TED演讲(音频版) 20179合集

Look at all those repeating base pairs: ATCG.

看看所有那些重复的碱基对:ATCG。

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Research articles

Remember, Evo2 has been trained on trillions of DNA base pairs.

记住,Evo2已经接受了数万亿个DNA碱基对的训练

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TED 2019度大会(双语)

Because in order to be stable in cells, the two strands of a DNA double helix have to form base pairs.

因为为了在细胞中稳定,DNA双螺旋的两条链必须形成碱基对。

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Research articles

They managed to insert this 765 base pair segment of DNA into the yeast genome, right?

他们设法将这 765 个碱基对的 DNA 片段插入酵母基因组中,对吧?

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TED-Ed(视频版)

Each person's DNA consists of about 6 billion base pairs stored in 23 pairs of chromosomes— 46 total.

每个人的 DNA 由大约 60 亿个碱基对组成,存储在 23 对染色体中——总共 46 条。

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学60秒-学美国人 20226合集

When Huda and Harry combined their data, they were able to narrow the location of their gene down to about one million base pairs.

Huda 和 Harry 合并数据后,他们就能将基因位置缩小到大概100万碱基对

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经济学人-

And some parts, particularly those where the same short pattern of base pairs is repeated over and over again, remain difficult to sequence well.

而且其中某些部分,尤其是那些短型碱基对被不断复制的位置,仍然很难准确测序。

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经济学人-

Rather than patenting every conceivable variant, the company claims jurisdiction over isolated DNA sequences, 15 base pairs long, that match short parts of the genes.

他们不是对每一有可能得到的基因突变体持有专利权,而是对一段分离到的基因序列持有专利权,这段基因序列含有15个碱基对

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经济学人-

Besides the low error rate, Dr Kedes requires that the sequence be complete-meaning that it includes at least 98% of the genome's base pairs.

除了错误率要低,德斯博士还要求测序结果必须是完整的,即至少包括人体98%的染色体碱基对。

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Osmosis-肌骨

Alright, so the dystrophin gene is a huge gene on the X-chromosome, that has 79 exons and is over 2 million base pairs in length.

抗肌萎缩蛋白基因是X染色体上一个庞大的基因,含有79个外显子,全长超过2000kbp(书上通常缩写为bp,碱基对)。

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TED演讲(视频版) 201811合集

All you have to remember from your high school biology is that the four natural letters pair together to form two base pairs.

你在高中生物学中所需要记住的就是四个自然字母配对在一起形成两个碱基对。

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Osmosis-遗传

Well, Cas9 recognizes a specific Protospacer Adjacent Motif or PAM for short which is a conserved 2-5 base pair sequence located near the crRNA complementary sequence.

Cas9很快会识别特定的" 原间隔序列邻近基序" (简称PAM);PAM是病毒位于crRNA互补序列附近的2-5保守的碱基序列。

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