Ankylosing spondylitis, also called Bechterew disease, is part of a group of diseases called seronegative spondyloarthropathies.

性脊柱炎也称Bechterew，是一类旧称为“血清阴性脊柱关”疾中一种。

In ankylosing spondylitis there's chronic inflammation of the intervertebral joints and the facet joints of the spine.

患有性脊柱炎时，椎间盘和关突关内存在炎症。

Inflammation and pain from ankylosing spondylitis is usually treated with non-steroidal anti-inflammatory drugs like ibuprofen.

性脊柱炎炎症和疼痛通常采用如布洛芬等非甾体类抗炎药来治疗。

Ankylosing spondylitis is a systemic inflammatory disease, so it can cause symptoms, like weight loss, fevers, and fatigue.

性脊柱炎是一种全身性炎症性疾，因此能够引起全身症状，如体重减轻、发热和疲劳。

Ankylosing spondylitis can be diagnosed using MRI, where there's typically erosion and narrowing of the joint spaces early on, and joint fusion later on.

利用MRI可诊断性脊柱炎，程早期通常可见关腔侵蚀和狭窄，晚期可见关融合。

Most individuals with ankylosing spondylitis have the gene HLA-B27, which is a gene that encodes for a specific type of MHC class I molecule.

许多性脊柱炎患者都携带HLA-B27基因，该基因能编码一种特定MHC Ⅰ类分子。

So ankylosing spondylitis is a chronic inflammatory disease that affects the vertebral joints and makes the spine really stiff, but can also cause inflammation in other parts of the body like the eyes and blood vessels.

因此，性脊柱炎是一种累及脊柱关并使脊柱变得僵慢性炎症性疾；它也会累及身体其他部位，如眼部和血管。