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Conclusion: The changes of circadian variation of blood pressure are associated with the role of sympathetic nerve and intracardial renin angiotensin system.

结论血压昼夜变化受交感神经与素血管紧张素系重作用有关。

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Renin, a proteolytic enzyme formed in the granules of the juxtaglomerular apparatus cells, catalyzes conversion of the protein angiotensinogen to angiotensin I, a decapeptide.

球旁体细胞颗粒内形成的一种蛋白水解酶,催化蛋白血管紧张素原转换为血管紧张Ⅰ,即十肽。

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WIL生活启示录

But, as I mentioned earlier, this renin angiotensin aldosterone system is stimulated by low salt intake.

但是,正如之前提到的,低盐饮食会导致 RAA 系统活跃。

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科学杂志:动物学

And to our surprise, they doubled and tripled the concentration of angiotensin in the blood.

惊讶的是,它使液中紧张的浓度翻倍甚至增至三倍。

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科学杂志:动物学

And then we decided to look at, are these neurons actually capable to transmit information from angiotensin.

于是定探究,这些神经元是否真的能够传递来自紧张的信息

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科学杂志:动物学

[Elena Gracheva] The next step was to check if neurons that detect angiotensin, are they actually sensitive to this hormone?

下一步是紧张的神经元是否真的对这种激素敏感?

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科学杂志:动物学

[Elena Gracheva] So, despite that they're sensitive to angiotensin, they cannot transmit this information downstream to different brain regions.

却无法将这一信息传递至下游的不同脑区。

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科学杂志:动物学

This is going to trigger the production of this hormone, angiotensin 2, along with its sidekick, aldosterone, which can stimulate sodium appetite.

这将触发这种激素——紧张2的生成,以及它的搭档——醛固酮的生成,后者可以刺激对钠的需求。

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科学杂志:动物学

[Maddy Junkins] And this suggests that they're detecting aldosterone and responding with sodium appetite, but they're not detecting angiotensin and responding with thirst.

这表明它能够测到醛固酮并产生对钠的需求,但它无法测到紧张并产生口渴反应。

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WIL生活启示录

This system begins with your liver releasing angiotensinogen, and, after a series of steps that you can read about in an endocrinology textbook, angiotensin I is produced.

该系统开始从肝脏释放管紧张素原,经过一系列步骤(请参考内分泌相关教材)之后,I 型紧张产生了。

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Crash Course 解剖生理学篇

Your kidneys cook up hormones like renin and angiotensin which help regulate levels of sodium and fluids in your body, and also help expand and constrict blood vessels.

你的肾脏会分泌肾素和紧张等荷尔蒙,这些荷尔蒙有助于调节体内钠和液体的水平,也有助于扩张和收缩管。

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Osmosis-泌尿

Along the same lines, drugs that reduce the effect of aldosterone can also cause hyperkalemia, and these are drugs like renin inhibitors, ACE inhibitors, angiotensin II receptor antagonists, selective aldosterone blockers, and potassium-sparing diuretics.

同理,可以降低醛固酮效能的药物也可以导致高钾症,例如肾素抑制剂、ACE抑制剂、紧张II受体拮抗剂、选择性醛固酮受体阻滞剂以及保钾利尿剂等。

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