NK cell will trigger effector functions(cytolysis) by KAR,if target cell loses appropriate ligands recognized by KIR.
如果靶细KIR所识别的体,NK细即KAR对靶细进行攻击。
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But when P! nk came through, I just… wasn't amid .
但当 P! nk 出现的时候,我其实......并没有很喜欢。
You guys slapt on P! nk, so now she's an honorary Australian.
你们对 P! nk 不不睬,所以她现在是光荣的澳大利亚人啦。
NK cells kill their target cells by releasing cytotoxic granules in their cytoplasm directly into the target cell.
NK通过释放质内的毒颗粒直接进入靶内,来杀死靶。
When I was young, there weren't many musicians or artists that were female that embodied what P! nk does.
我小的时候没有很多音乐家或艺术家是 P! nk 这样具有象征性的女性。
If the pathogen was a virus, NK cells would help destroy the infected cells at this point.
如果病原是病毒,此时NK会帮助摧毁被感染的。
B and T cells make up the adaptive immune system, while NK cells are part of the innate immune system.
B和T组成了适应性免疫系统,而NK是固有免疫系统的一部分。
Do you th nk you've got what it takes? Well, do you?
你以为这样就能混进来吗? 是不是?
So taking out the NK contribution didn't really hurt the overall defense much?
所以去除NK的贡献对整影响不大?
I had forgotten that P! nk had recorded it and that she had released it on her greatest hits album in 2010.
我都忘了P! nk曾录制过这首歌,她在2010年把它收录在了她的精选专辑中。
It points directly to the innate immune system's premier killers, natural killer cells, NK cells.
它直接指向先天免疫系统的主要杀手——自然杀伤,即NK。
Yes , I can , such as CCS , ABS , LR , NK and so on .
能,比如中国船级社,美国船级社,劳氏船级社,日本船级社等。
Ah, the NK cells make a comeback.
啊,自然杀伤又回来了。
The leptomeninges they found contain NK cells in various states, some naive, some activated, some proliferating.
他们发现软脑膜中存在处于不同状态的自然杀伤,有些是未激活的,有些已激活,有些正在增殖。
So how does the orchestrator DC talk to the executioner NK cell?
那么,指挥者树突状是如何与执行者自然杀伤沟通的呢?
They're huge for NK cells, right?
对NK来说非常重要,对吧?
Did they see evidence of this DC-to-NK communication in actual human LM patients?
他们是否在实际的人类脑膜转移患者中观察到了树突状向自然杀伤传递信号的证据?
Definitive proof that the NK cell is the one actually carrying out the execution order.
确凿的证据表明,自然杀伤才是真正执行清除指令的。
NK cells are large lymphocytes with granules and they target cells infected with intracellular organisms, like viruses, as well as cells that pose a threat like cancer cells.
NK是有颗粒的大淋巴,它们靶向被内病原(如病毒)感染的,还有像癌这样构成威胁的。
Then, into that system, they introduced an antibody treatment that specifically depletes NK cells, gets rid of them.
然后,他们向该系统中引入了一种特异性耗竭NK的抗治疗,将这些清除掉。
Depleting the NK cells completely abolished the tumor control and the survival benefit provided by the IFNO boost.
耗尽NK后,IFNγ增强所带来的肿瘤控制和生存获益完全消失。
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